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New Medicine

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Robotic kidney transplant done at Safdarjung Hospital, doctors claim first for a govt facility
The Print

A 39-year-old man underwent a robotic kidney transplant at Safdarjung hospital here, which doctors claimed to be the first such surgery to have been performed at a central government facility in the country.

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The SSI Mantra: India's own surgical robot boasts cheaper price tag
Business Standard

India now has a homegrown robotic surgery system that holds out promise of less prohibitive costs in a niche category of medical treatment, thanks to the efforts of a US returnee cardiac surgeon and his tech team. Designed in India, the SSI Mantra aims to rival the widely popular da Vinci surgical system, which is manufactured by global market leader Intuitive Surgical, and costs less than a third of the latter. The SSI Mantra costs around Rs 4.5 crore and da Vinci Rs 15 crore. It is already being deployed at the Rajiv Gandhi Cancer Institute and Research Centre in New Delhi, where it was installed last month and has so far performed 22 complex surgeries.

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Researchers develop gene therapy for rare ciliopathy
ANI News

Researchers have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

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Study probes how intestine repairs damaged tissue
ANI News

Researchers in a new study discovered a component in the intestine that plays a crucial role in repairing damaged tissue. The research led by investigators at Cedars-Sinai and the University of California, San Francisco (UCSF) and the findings were published in the journal Cell Stem Cell.

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Children, teenagers getting spinal surgery don't need so many opioids: Study
ANI News

According to a study, children and teenagers with scoliosis who undergo spinal fusion can still be given an acceptable amount of pain medication while using fewer opioids.

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Study finds direct connection between brain and vagus nerve
ANI News

A direct connection between vagus nerve stimulation and its linkage to the brain's learning centres has been demonstrated by researchers at the University of Colorado Anschutz Medical Campus. The finding could pave the way for therapies that strengthen memory retention in both healthy and damaged neural systems. The study was published last week in the journal Neuron.

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India’s first Transcatheter Mitral Valve repair performed at Apollo Hospitals Chennai
Telangana Today

Three senior citizens with end-stage heart failure recently underwent advanced fourth generation mitral valve repair at Apollo Hospitals in Chennai. A release by the hospital said the fourth generation “MitraClip Transcatheter Mitral Valve Repair System“ allowed greater flexibility for doctors to perform complex valve repairs based a patient’s mitral valve anatomy.

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Researchers find fabrication of artificial heart for transplant
The Print

Unlike other organs, the heart cannot heal itself after injury. Heart disease is the top cause of mortality in the U.S and is particularly deadly. For this reason, tissue engineering will be crucial for the development of cardiac medicine, ultimately leading to the mass production of a wholesale fabrication of an entire human heart for transplant. The findings of the research were published in Science.

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Punjab man undergoes complex kidney transplant at Delhi hospital
The Print

A 29-year-old man received a new lease of life after undergoing renal autotransplant, a rare procedure in which the patient's own kidney is taken out and then transplanted into a different part of the body. The patient, a resident of Punjab, has a history of stones in the left ureter (pipe connecting kidney and urinary bladder). A local doctor in his home state had tried to remove the stone but during the process, 25-26 cm of left ureter also came out along with the stone, said Dr Vipin Tyagi, senior consultant, urology and kidney transplant at Sri Ganga Ram hospital.

Global coverage

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Talks on second-gen COVID vaccine will take months and could fail, Valneva warns
Zawya

Current talks with a potential partner on its COVID-19 jab could take several months and might not succeed, French drugmaker Valneva warned on Monday, saying it would only produce a second-generation vaccine if it obtains the necessary funding. The French company has struggled to bring its COVID-19 vaccine to the market and compete with the products of larger rivals like AstraZeneca, Moderna or BioNTech/Pfizer. Its shares have lost almost 80 percent since peaking at the end of 2021.

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Phase 3 trial evaluating antiviral tecovirimat with monkeypox infection begins in US
Pharma Biz

A phase 3 clinical trial evaluating the antiviral tecovirimat, also known as Tpoxx, is now enrolling adults and children with monkeypox infection in the United States. Study investigators aim to enroll more than 500 people from clinical research sites nationwide.

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AstraZeneca, Merck announce positive results from phase 3 PAOLA-1 & SOLO-1 trials of Lynparza in combo with bevacizumab to treat first-line advanced ovarian cancer
Pharma Biz

AstraZeneca and Merck, known as announced long-term follow-up results from the phase 3 PAOLA-1 and SOLO-1 trials in first-line advanced ovarian cancer, which represent the longest-term data for any PARP inhibitor in this setting.

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FDA panel backs much-debated ALS drug in rare, 2nd review
APN News

A panel of federal health advisers voted Wednesday to recommend approval for an experimental drug to treat Lou Gehrig’s disease, a remarkable turnaround for the much-debated medication that was previously rejected by the same group earlier this year.

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US FDA advisory committee to review GSK’s NDA for daprodustat in anaemia of chronic kidney disease
Pharma Biz

GSK plc announced that the US Food and Drug Administration (FDA) will convene a meeting of the Cardiovascular and Renal Drugs Advisory Committee (CRDAC) to review the New Drug Application (NDA) for daprodustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) under regulatory review for the potential treatment of anaemia due to chronic kidney disease (CKD) in adult patients on dialysis and not on dialysis.

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WHO and partners launch new online resource to advance STI vaccine development
Pharma Biz

The first online portal on vaccine development for sexually transmitted infections (STIs) was launched at the 23rd IUSTI World Congress. The portal, STI Watch contains technically sound and updated information on the most common STIs and the vaccine development status for each.

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New Dupixent data at EADV 2022 adds to body of evidence across multiple inflammatory skin diseases
Pharma Biz

Twenty-five scientific abstracts evaluating Dupixent (dupilumab) in moderate-to-severe atopic dermatitis from infancy to adulthood, prurigo nodularis and chronic spontaneous urticaria will be presented at the European Academy of Dermatology and Venereology (EADV) 2022 Congress from September 7 to 10.

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Onera introduces innovative sleep diagnostics solution in Europe
Pharma Biz

Onera Health, a leader in transforming sleep medicine and remote monitoring, announced the official launch of its ground-breaking solution to diagnose sleep disorders in Europe. The service is based on the companies’ CE-marked and FDA-cleared Onera Sleep Test System and the Onera Digital Health Platform. It allows sleep professionals to conduct sleep studies at the comfort of the patients’ home while maintaining clinical-grade quality as with in-lab diagnostics.

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Gilead announces positive data from phase 3 TROPiCS-02 study
Pharma Biz

Gilead Sciences, Inc. announced new data from a post hoc subgroup analysis from the phase 3 TROPiCS-02 study evaluating Trodelvy (sacituzumab govitecan-hziy) versus comparator chemotherapies (physicians’ choice of chemotherapy, TPC) in patients with HR+/HER2- metastatic breast cancer who progressed on endocrine-based therapies and at least two chemotherapies.

Doctors & Hospitals

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Aesthetic surgeries to be done by registered medical practitioners only: NMC guidelines
The Print

Aesthetic procedures including hair transplants should be carried out only by registered medical professionals having adequate training, the National Medical Commission (NMC) said and underlined they should not be attempted by watching demonstrations in workshops or on YouTube.

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Safdarjung conducts robotic cardiothoracic surgery, third in Sept
The Morung Express

Safdarjung Hospital has become the first central government-run health facility to conduct a robotic cardiothoracic surgery. The hospital, which used the technology for the first time this September, has so far conducted three such surgeries, the authorities said. The technology was procured in October 2019 for gynaecological, urological and cardiothoracic vascular surgeries. “However, in the past two years, the programme couldn’t be started due to Covid-19. In India, there was no such established cardio programme when we bought the robotic technology. Even now, only a few hospitals have it,” said Dr Anubhav Gupta, head of the department of cardiothoracic vascular surgery (CTVS).

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AIIMS starts testing samples to detect monkeypox virus
Acetech News

AIIMS Delhi has started conducting tests of samples collected to detect monkeypox virus. The AIIMS virology lab under the microbiology department is one of the 15 labs authorised across the country for the test by the department of health research-Indian Council of Medical Research.

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Private ward at AIIMS to cost more due to GST on room rent above 5k
The New Indian Express

AIIMS Delhi on Thursday announced a raise in the charges of its private ward rooms. The move comes following a recent decision by the GST Council to levy a 5 percent tax on hospital room rent exceeding Rs 5,000 per day. The revised charge will be effective from July 18, as per government notification.

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IPSC Pain and Spine Hospital introduces cooled radiofrequency ablation for chronic pain management
Pharma Biz

Radiofrequency ablation (RFA) is offering new hope to patients of chronic pain such as back pain, neck pain, facial pain, and joint pain like that of shoulder and knee. The technique was in the limelight recently when tennis star Rafael Nadal underwent the procedure to cure his chronic foot pain after all other treatment options failed.

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Delhi’s Rajiv Gandhi Cancer Institute gets first indigenously developed Surgical Robotic System, SSI-Mantra
Financial Express

Rajiv Gandhi Cancer Institute and Research Center (RGCI), New Delhi gets its first-ever Made-in-India Surgical Robotic System, SSI-Mantra which is developed by med-tech start-up SS Innovations. On Thursday, robotic cardiac surgeon Dr. Sudhir P Srivastava and creator of SSI Mantra, along with Dr. Sudhir Rawal, Medical Director, RGCI announced the official launch and acquisition of the first model of the indigenous surgical robotic system. The Gurugram-based company claims that it is cheaper, more advanced, and more efficient than the US FDA-approved Da Vinci system which was approved for use in India in 2000. In 2002, India’s first robotic cardiac surgery was conducted with the Da Vinci system, and the first urological surgery in 2006.

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Madhavbaug’s Khopoli Hospital gets NABH accreditation
Pharma Biz

Madhavbaug Cardiac care center and Hospitals-- the flagship brand of Vaidya Sane Ayurved Laboratories Ltd, a specialist in treating and reversing cardiac related ailments, receives NABH accreditation for its state of the art hospital located at Khopoli, Maharashtra.  

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As pandemic ebbs, hospitals see a rise in elective surgeries
Pehal News

Private hospitals and clinics throughout the board are seeing a 20-30 percent improve in elective procedures in contrast with pre-pandemic ranges, as individuals who have delayed or cancelled surgeries for concern of Covid infections in the final two years at the moment are queuing as much as get these executed.

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Fortis launched cancer care hospital in South Delhi
Healthwire

Fortis Healthcare today launched the State-of-the-Art Patient-Centric – Fortis Cancer Institute at Defence Colony, New Delhi.

Drug Discovery

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IIT Guwahati develops cancer drug carrier
The Telegraph

IIT Guwahati has developed a drug carrier that will safely deliver drugs to cancerous cells.  The premier institute said on Monday that the molecules developed by the IIT-G researchers self-assemble as capsules to hold the drug, which then attaches only to cancer cells. When infrared light is shone on it, the shell breaks and releases the encapsulated drug into the cancerous cell. The researchers believe their approach would allow the development of drug carriers for chemotherapy with “enhanced efficacy and negligible side effects”. The problem with existing chemotherapeutic drugs is that they kill healthy cells of the body in addition to cancerous cells, leading to numerous undesirable side effects.

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New drug helps relieve eczema’s terrible itch
The Print

Researchers involved in a new multi-site international phase III study led by Northwestern Medicine found that a new drug was highly effective in reducing the signs and symptoms of moderate-to-severe eczema. This is the first study to treat moderate-to-severe eczema in infants and children 6 months to 5 years of age with a biologic drug (monoclonal antibody) instead of immune-suppressing medications.

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New type 2 diabetes drug achieves blood sugar, weight targets faster: Research
ANI News

New research evaluating the time taken to reach blood glucose targets indicates that tirzepatide achieves blood sugar control and weight-loss goals faster than existing diabetes drugs. The latest analyses of the SURPASS-2 and SURPASS-3 trials, being presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden (19-23 Sept).

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Researchers develop drug that marks cancer cells for destruction by immune system
ANI News

Tumour cells are infamous for their ability to evade the human immune system; they construct physical barriers, disguise themselves, and handcuff the immune system with molecular tricks. Now, UC San Francisco researchers have created a drug that overcomes some of these hurdles by marking cancer cells for elimination by the immune system.

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Researchers find opioid use after lung cancer surgery have association with risk of death
ANI News

Long-term opioid use to relieve pain following lung cancer surgery is associated with a 40 percent increased risk of death from any cause within the next two years. The findings of the research were published online in the journal Regional Anesthesia & Pain Medicine.

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Researchers find that anti-diarrheal drug might treat core ASD symptoms
The Print

Currently, there are no medication treatments for the basic symptoms of autism spectrum disorder (ASD), may an existing drug provide a new treatment, even if it previously had no association with ASD? A new study posed this question. The researchers developed a computer model that included proteins involved in ASD as well as their interactions.

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New game-changing obesity drug dramatically reduces risk of Type 2 Diabetes
Scitech Daily

The risk of type 2 diabetes is reduced by more than half by weekly injections of the new obesity drug Wegovy (semaglutide). This is according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden (September 19-23). Semaglutide was recently approved in the US by the Food and Drug Administration as an obesity treatment[1] and has been provisionally approved by The National Institute for Health and Care Excellence to treat obesity in England.

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AI may help reduce common drug side effects
Express Pharma

A team of researchers has developed a tool which uses natural language processing, an Artificial Intelligence (AI) methodology, and chemical structure analysis to measure the harmful effects of medicines, according to the study. The new tool is designed to calculate which medicines are more likely to experience adverse anticholinergic side effects, which impact the brain by blocking a key neurotransmitter called acetylcholine.

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AstraZeneca’s dapagliflozin shown to reduce CV fatality in DELIVER phase III trial
Pharma Biz

AstraZeneca’s detailed results from the DELIVER phase III trial showed dapagliflozin significantly reduced the composite of cardiovascular (CV) fatality  or worsening heart failure (HF) in patients with HF and mildly reduced or preserved ejection fraction (EF), compared to placebo.

Becares-Weekly

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Biological E's Corbevax Caccine to Cost ₹145 to Govt, ₹990 in Market
Live Mint

Hyderabad-based pharmaceuticals and biologics major Biological E Ltd has priced its Corbevax anti-Covid vaccine at ₹990 (inclusive of taxes and vaccine administration charges) in the private market, and ₹145 for the government vaccination programme, news agency PTI quoted the firm's managing director Mahima Datla as saying.  Currently, the vaccine is being used for the inoculation of children in the 12 to 14 age group. In view of this, the company has also expressed confidence over getting emergency use authorisation for use of its vaccine in children in the age group of 5-12 years. Biological E said its multiple manufacturing units in Hyderabad are fully qualified to enable the production of around 1 billion dosages of Corbevax annually and it is geared up to meet any increase in demand.

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Corbevax vaccine for kids: Everything you need to know about this Covid jab
Live Mint

Biological E Limited's Corbevax is being administered to children in the age group 12-14 in India. This age group got the Indian government's nod to be receive vaccine against the novel coronavirus from 16 March, Wednesday. These children have to register for getting the vaccine on the CoWIN portal. India's third indigenous anti-Covid vaccine has been manufactured by Hyderabad-based Biological E Limited. Biological E has supplied 5 crore doses of Corbevax to the Centre, which has then distributed the same to states.

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Corbevax vaccine for 5-12 years: Confident of getting EUA, Biological E says
Live Mint

Biological E seems confident regarding getting emergency use authorisation for use of its COVID vaccine Corbevax among children in the age group of 5-12 years. Currently, the vaccine is inoculated among children in the age group of 12 to 14 years The Hyderabad-based company Is qualified to produce around 1 billion dosages of Corbevax annually and it is geared up to meet any increase in demand. Currently, the company has produced 30 crore vaccines as part of its commitment made to the Government of India, with 5 crore dosages already supplied.

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Ready with 30 crore doses, can scale up production if needed: Corbevax makers
The Indian Express

Biotech firm Biological E. Limited is geared to facilitate the first phase of the vaccination drive for the 12-15 age group and is ready with 30 crore doses of which five crore has been rolled out to 17 different sites in the country, said a top official of the firm. "This is the most affordable COVID-19 vaccine for the Government of India which is providing free vaccination to all eligible citizens. The pricing of CORBEVAX in the private market will be Rs 800 (and inclusive of all taxes and vaccine administration charges will cost Rs 990) The vaccine is being sold at Rs 145 per dose to the government," Mahima Datla, managing director of Biological E. Limited said at a virtual media interaction on Wednesday. "We have an annual production capacity upto one billion vaccines," Datla said. The firm collaborated with the Texas Children's Hospital and the Baylor College to develop Corbevax vaccine. Dynavax, Inc from USA supported Corbevax development by providing the adjuvant and THSTI Delhi conducted key immunogenicity testing as part of a comprehensive clinical trial development plan.

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Covid-19: 12-14 vaccination drive off to slow start in Delhi; pick-up likely after Holi
The Times of India

Only about 3,800 children aged between 12 and 14 were vaccinated against Covid-19 in the city on Wednesday, the first day of vaccination for this cohort in the country. All the children were administered Corbevax, India's first indigenously developed protein subunit vaccine against Covid-19, made by Biological E. Each dose in the private market will cost Rs 800 per dose, excluding GST, and around Rs 990, including taxes and administration charges. For the government, the price will be Rs 145. There are nearly 6.2 lakh children in this age group in Delhi who are eligible for the vaccine. Hospital officials said the first day saw a lukewarm response; footfall is expected to pick up after Holi.

Medical Specialties

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Robotic kidney transplant done at Safdarjung Hospital, doctors claim first for a govt facility
The Print

A 39-year-old man underwent a robotic kidney transplant at Safdarjung hospital here, which doctors claimed to be the first such surgery to have been performed at a central government facility in the country.

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The SSI Mantra: India's own surgical robot boasts cheaper price tag
Business Standard

India now has a homegrown robotic surgery system that holds out promise of less prohibitive costs in a niche category of medical treatment, thanks to the efforts of a US returnee cardiac surgeon and his tech team. Designed in India, the SSI Mantra aims to rival the widely popular da Vinci surgical system, which is manufactured by global market leader Intuitive Surgical, and costs less than a third of the latter. The SSI Mantra costs around Rs 4.5 crore and da Vinci Rs 15 crore. It is already being deployed at the Rajiv Gandhi Cancer Institute and Research Centre in New Delhi, where it was installed last month and has so far performed 22 complex surgeries.

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Researchers develop gene therapy for rare ciliopathy
ANI News

Researchers have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

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Study probes how intestine repairs damaged tissue
ANI News

Researchers in a new study discovered a component in the intestine that plays a crucial role in repairing damaged tissue. The research led by investigators at Cedars-Sinai and the University of California, San Francisco (UCSF) and the findings were published in the journal Cell Stem Cell.

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Children, teenagers getting spinal surgery don't need so many opioids: Study
ANI News

According to a study, children and teenagers with scoliosis who undergo spinal fusion can still be given an acceptable amount of pain medication while using fewer opioids.

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Study finds direct connection between brain and vagus nerve
ANI News

A direct connection between vagus nerve stimulation and its linkage to the brain's learning centres has been demonstrated by researchers at the University of Colorado Anschutz Medical Campus. The finding could pave the way for therapies that strengthen memory retention in both healthy and damaged neural systems. The study was published last week in the journal Neuron.

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India’s first Transcatheter Mitral Valve repair performed at Apollo Hospitals Chennai
Telangana Today

Three senior citizens with end-stage heart failure recently underwent advanced fourth generation mitral valve repair at Apollo Hospitals in Chennai. A release by the hospital said the fourth generation “MitraClip Transcatheter Mitral Valve Repair System“ allowed greater flexibility for doctors to perform complex valve repairs based a patient’s mitral valve anatomy.

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Researchers find fabrication of artificial heart for transplant
The Print

Unlike other organs, the heart cannot heal itself after injury. Heart disease is the top cause of mortality in the U.S and is particularly deadly. For this reason, tissue engineering will be crucial for the development of cardiac medicine, ultimately leading to the mass production of a wholesale fabrication of an entire human heart for transplant. The findings of the research were published in Science.

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Punjab man undergoes complex kidney transplant at Delhi hospital
The Print

A 29-year-old man received a new lease of life after undergoing renal autotransplant, a rare procedure in which the patient's own kidney is taken out and then transplanted into a different part of the body. The patient, a resident of Punjab, has a history of stones in the left ureter (pipe connecting kidney and urinary bladder). A local doctor in his home state had tried to remove the stone but during the process, 25-26 cm of left ureter also came out along with the stone, said Dr Vipin Tyagi, senior consultant, urology and kidney transplant at Sri Ganga Ram hospital.

Vaccine Launch & Research

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New study sees possible link between aluminum in childhood vaccines and risk of asthma, but caveats abound
Stat News

A study funded by the US government has tried understanding if the aluminum in children vaccine tends to affect and cause asthma and other allergies in the toddlers. The aluminum is an additive used in children vaccine. Aluminum has been used in some vaccines since the 1930s, as an ingredient — called an adjuvant — that provokes stronger immune protection.

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FIP issues new guidance on safety of co-administration of Covid-19 and flu vaccines calls for pharmacists’ involvement
Pharma Biz

International Pharmaceutical Federation (FIP) has now issued a new guidance on “Optimising vaccination through co-administration of influenza and Covid-19 vaccines’  Vaccination is a key strategy in the prevention of respiratory infectious diseases like Covid-19 and influenza, and therefore improves people’s quality of life. Administering vaccines against Covid-19 and flu at the same time increases uptake of each vaccine and increases protection against both diseases, said FIP.

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19 lakh doses of Corbevax administered
The Times of India

People aged above 18 years are taking Corbevax as a precaution Covid-19 dose with great enthusiasm. In the state, around 32 percent of the doses administered as precaution doses were Corbevax vaccines, which means that 32 percent of the people who had received first two doses of Covishield or first two doses of Covaxin opted for Corbevax as a precautionary dose as they did not receive Covishield or Covaxin as precautionary doses. The government had approved Biological E's Corbevax as a precautionary dose on August 10. Since then, 19,73,313 Corbevax doses have already been used as precautionary doses.

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Vaccinated people infected by Omicron have four times greater protection: Study
Financial Express

Vaccinated people who were infected by the first Omicron subvariants have four times greater protection than jabbed people who did not catch the COVID-19 infection, according to a study. The research, published recently in the New England Journal of Medicine, analysed the probability of vaccinated people becoming infected with the subvariant BA.5 currently in circulation. The researchers in Portugal estimated the degree of protection conferred by infections with previous variants and used real-world data. “Vaccinated people who were infected by Omicron subvariants BA.1 and BA.2 have a protection against infection with subvariant BA.5, in circulation since June, about four times greater than vaccinated people who were not infected at any time,” said Luis Graca, a professor at the University of Lisbon.

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India launches its first cervical cancer vaccine, Serum likely to keep cost ₹200-400
Pehal News

The Central government launched India first vaccine against cervical cancer--Quadrivalent Human Papillomavirus vaccine (qHPV), has been developed by the Serum Institute of India (SII) and the Department of Biotechnology (DBT) on Thursday. According to the Serum Institute, the vaccine is likely to cost 200-400 per dose. Adar Poonawalla, CEO, Serum Institute of India said “We will announce the price of the vaccine in a few months. It will be around ₹200-400. We will start production by November and December and final decision on rates will be discussed with the government."

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SEC Recommends Biological E’s 14-Valent Pneumococcal Conjugate Vaccine for Infants
The Print

Hyderabad-based vaccines manufacturer Biological E Limited announced on Thursday that the Subject Expert Committee (SEC) of the Central Drugs Standard Control Organization (CDSCO) reviewed and approved the Phase III infants clinical trial data and recommended for the manufacture of its 14-valent paediatric vaccine (investigational pneumococcal polysaccharide conjugate vaccine PCV14) against S pneumoniae infection in a single dose and multi-dose presentations. The company said the PCV14 can be administered to infants at 6, 10 and 14 weeks of age.

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Novavax Covid-19 vaccine Adjuvanted gets expanded approval in US
Nasdaq

Novavax says the US Food and Drug Administration (FDA) has granted expanded emergency use authorisation for its Covid-19 vaccine Adjuvanted for adolescents aged between 12-17 years. The US company said the vaccine was the first protein-based Covid-19 jab authorised in the US, dpa news agency reported. Doses of the Adjuvanted are available for use in adolescents upon the Centers for Disease Control and Prevention's (CDC) recommendation, the company noted.

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NTAGI has Found Corbevax Efficient as a Booster, Govt may Soon Recommend It
Pehal News

The government may allow using a different vaccine as third dose for those who are fully vaccinated with either Covishield or Covaxin. The National Technical Advisory Group on Immunisation (NTAGI) which reviewed the data of Corbevax earlier had found significant antibody response when it was given as a third dose to those who have received two doses of Covishield and covaxin. "We reviewed the data and found significant antibody response in both the groups i.e those who have got Covishield and Covaxin," a person in the know said. Adding that it's inclusion as a heterologous booster will be made by the government. Corbevax was cleared by the Drug Controller General of India as a booster.

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WHO publishes updated global Covid-19 vaccination strategy in response to spread of Omicron subvariants
Pharma Biz

WHO published an update to the Global Covid-19 Vaccination Strategy, in response to the spread of Omicron subvariants, advances in vaccine evidence, and lessons from the global vaccination programme.

Disease Studies

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New technologies can be key to producing effective therapies for fatal muscle disease: Study
The Print

A genetic mutation causes Duchenne muscular dystrophy (DMD), which affects one in every 5,000 boys born. Because the affected gene is located on the X chromosome, girls are carriers of the mutant gene but only very rarely develop the disease (one in about 50 million).

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H1N1-Covid combo seen in Kerala patients
The Times of India

Co-infection of Covid-19 with other respiratory pathogens - H1N1 flu - a subtype of influenza A is now being seen in patients in Kerala. Although, at the moment, a low proportion of Covid-19 patients have influenza co-infection, however, it cannot be ignored especially in high-risk individuals and the elderly.

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Researchers explain the cause of autoimmunity in patients with type 1 diabetes
ANI News

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details of the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown. In a new study, researchers present a testable hypothesis to explain the initiation of autoimmunity. If validated, this would allow early detection and possible prevention of T1D in susceptible individuals.

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Urine test for detecting TB in HIV patients shows promising results
The Times of India

A rapid urine test that can detect tuberculosis in under 30 minutes has shown significant results when tested in patients with advanced HIV as it could pick up cases that may have gone undiagnosed otherwise. The Mumbai District AIDS Control Society (MDACS) used the lateral flow urine lipoarabinomannan (LF-LAM) test to check for tuberculosis in 2,390 HIV patients with advanced disease undergoing treatment at 17 treatment centres in the city.

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Rising temperature can lead to weight loss among heart failure patients, study found
Financial Express

A nationwide study in France has reported that during the 2019 heatwave, increased temperatures were closely linked with weight loss in heart failure patients, indicating a worsening of their condition. The findings of the study are published today in ESC Heart Failure, a journal of the European Society of Cardiology.

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People infected with Covid at risk of long-term brain injury: Study
US News

A study has revealed that people who have had Covid-19 infection are at a higher risk of a long-term brain injury, a year later compared to the people who have never been infected with the virus. The year-long study, published in Nature Medicine, assessed brain health across 44 different disorders using medical records without patient identifiers from millions of US veterans. Brain and other neurological disorders occurred in 7 percent more of those who had been infected with Covid compared with a similar group of veterans who had never been infected. That translates into roughly 6.6 million Americans who had brain impairments linked with their Covid infections, the study said.

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Diabetes cases set to double globally, warns study
Pehal News

Number of individuals dwelling with Type 1 diabetes internationally is set to virtually double by 2040 to between 13.5 million and 17.4 million, a modelling study printed in medical journal Lancet Diabetes and Endocrinology has mentioned. There had been an estimated 8.4 million individuals dwelling with Type 1 diabetes (T1D) in 2021, it mentioned, highlighting the necessity for enhancing the usual of care of such individuals internationally.

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Study reveals process of how Parkinson’s disease spreads in brain
The Print

According to a new study led by Weill Cornell Medicine researchers, aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson’s disease via a cellular waste-ejection process.

 

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Risk of blood clots remains for almost a year after COVID-19 infection, study suggests
MLO

COVID-19 infection increases the risk of potentially life-threatening blood clots for at least 49 weeks, according to a new study of health records of 48 million unvaccinated adults from the first wave of the pandemic. The findings suggest that the COVID-19 pandemic may have led to an additional 10,500 cases of heart attacks, strokes and other blood clot complications such as deep vein thrombosis in England and Wales in 2020 alone, although the excess risk to individuals remains small and reduces over time.

Health Services

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Assam CM inaugurates second ultramodern radiotherapy unit in cancer care centre of Guwahati city hospital
ANI News

Assam Chief Minister Himanta Biswa Sarma on Saturday inaugurated the second ultramodern radiotherapy unit in the cancer care centre of Health City Hospital in Guwahati.

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Centre caps processing charges by private blood banks
MSN

When you donate blood, it is not transfused into a needy patient directly. The donated blood, also referred to as whole blood, is processed or spun in centrifuges to separate it into transfusable components. This includes red cells, platelets, and plasma. The exercise is referred to as blood processing and it comes at a cost. In order to standardise charges and put a cap on it, the Centre has recently released a detailed guideline. It states that private blood banks cannot charge more than Rs 1,550 for processing whole blood.

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WHO launches new guide for integration of perinatal mental health in maternal and child health services
Pharma Biz

Life altering moments like pregnancy, birth, and early parenthood can be stressful for women and their partners. As a result, women may undergo a period of poor mental health or witness a worsening of previous mental health conditions.

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Portal launched recently provides info on blood availability across country: Mandaviya
The Print

Union Health Minister Mansukh Laxmanbhai Mandaviya on Friday said that a web portal has recently been created to provide information on the blood types available in the banks across the country, thus giving a momentum to the voluntary blood donation movement.

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Wipro GE Healthcare launches its first ‘AI-enabled Made-in-India’ Cath lab for advanced cardiac care in country
Financial Express

GE Healthcare on Monday announced the launch of its first ‘Made in India’, ‘AI-powered’ Cath lab – Optima IGS 320 to advance cardiac care in India. According to the company’s press statement, the Cath lab is built at Wipro GE Healthcare’s new factory launched under the Production Linked Incentive (PLI) scheme in Bengaluru. In India, non-communicable diseases (NCDs) contribute to 60 percent of all deaths, of which, 82 percent occur due to cardiovascular diseases (CVDs), chronic respiratory diseases, cancer, and diabetes.

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Govt issues draft guidelines to improve working conditions of nurses in healthcare institutions
The Print

The Union health ministry has issued draft guidelines, proposing annual health check-ups, a creche facility and work hours not exceeding 40 in a week, among other measures, to improve the working conditions of nurses in all healthcare institutions. It has also recommended that all healthcare establishments may, as far as possible, provide accommodation to their nursing staff within or near their premises.

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Gap between 2nd dose and precaution dose of Covid vaccines reduced on NTAGI’s advice: Govt
Financial Express

Based on the recommendations made by the National Technical Advisory Group on Immunisation (NTAGI), the interval between the second and the precaution dose of COVID-19 vaccines was revised from nine months to six months for all beneficiaries aged 18 years and above from July 6, the government informed Parliament on Friday. In a written reply to a question in the Lok Sabha, Minister of State for Health Bharati Pravin Pawar said as on August 1, a total of 9.07 crore (13 percent) precaution doses of the Covid vaccines were administered against the due beneficiaries.

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Portal with TB-related data from all over India to be launched: Health Minister Mansukh Mandaviya
The Print

A new portal that captures detailed information on the data related to tuberculosis from all over the country and would be accessible to everyone is going to be launched soon, Union Health Minister Mansukh Mandaviya has said.

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Govt releases Dos, Dont’s over preventing monkeypox
The Pioneer

Treading cautiously as cases of monkeypox rise  gradually in the country, the Union Health Ministry on Wednesday released a list of Dos and Don'ts to avoid contracting the disease which also urged people not to stigmatise virus-infected as well as suspected patients. “Do not believe any rumour or misinformation," the guidelines said, underlining that anyone can catch the virus if they have had prolonged or repeated contact with an infected individual. So far, nine cases have been reported in the country— four from Delhi and five from Kerala. One person of African origin has succumbed to the infection. Among the Dos, the Ministry advised isolating the infected person from others so that the disease does not spread.

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